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Episode · Jun 26, 2026 · 1 hr 31 min

He Fought for a World Title with Lyme Disease

with Mike Lee

Mike Lee is a former professional boxer who fought for a world title while struggling with Lyme disease and autoimmune illness.

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“I had this sense of relief where you don't have to do this anymore.”
Mike Lee

Summary

Mike Lee tells Ken Rideout how boxing became part of his life in Chicago, from Notre Dame’s Bengal Bouts and the Golden Gloves to Top Rank and big cards at Madison Square Garden and Cowboys Stadium. He says his father’s expectations drove him to keep fighting, even after breaking a rib during a world-title bout. While preparing for Caleb Plant, Lee was cutting weight and managing severe pain, but later admitted relief when his only professional loss ended the pressure to keep going.

Lee describes years of fatigue, inflammation, and back pain that doctors first treated as ankylosing spondylitis before he was diagnosed with Lyme disease and mast cell activation syndrome. After trying multiple medications, he shifted toward functional medicine and started Soul CBD with his sister, later adding the Out of Office THC line. He and Ken discuss life after boxing, pain relief, health choices, and building work beyond the ring.

Show notes

He graduated from Notre Dame, signed with Top Rank, fought at Madison Square Garden and Cowboys Stadium, starred in national Subway commercials, and earned a shot at a world title.

What almost nobody saw was what was happening behind the scenes.

For years Mike battled chronic pain, autoimmune disease, misdiagnoses, and Lyme disease while trying to keep his career alive. He fought through broken ribs, endless medications, and training camps where his body was telling him to stop long before his mind would listen.

In this conversation, Mike opens up about growing up in Chicago, the pressure to make his father proud, becoming one of boxing’s top contenders, the relief that came after his only professional loss, finding purpose beyond the ring, and why he now believes health is the greatest fight of all.

This is a conversation about identity, resilience, and knowing when enough is enough.

Read the transcript

Transcript

Made from YouTube's automatic captions and lightly corrected, so a few words and names may be off. Click a time to play the video from there.

Ken Rideout

All right, today's very special guest, my friend and former middleweight or super middleweight.

Mike Lee

Super middleweight and light heavyweight.

Ken Rideout

Super middleweight and light heavyweight champion of the world and Notre Dame graduate, the great Mikey Lee. Mike, thanks for being here.

Mike Lee

It's great to see you. Yeah.

Ken Rideout

What was your ring nickname?

Mike Lee

I never had one. It's funny. Right when I turned pro with with Top Rank, people were trying to give me different names. I just never had one, man. And so I always said like, if you have something in mind, let's run with it.

Ken Rideout

Well, you had the Subway deal, which was a big deal.

Mike Lee

Yeah. Yeah. Um, ended up getting the the Subway deal. It was really cool early on in my career. It's funny what happened with that. I had a a fight on ESPN and I I think the the CMO at the time and some of the leadership were um Notre Dame graduates and affiliates.

So, I said on ESPN, unbeknownst to that, anyone was watching, that I'm very superstitious. And what I used to do even in the amateurs before fights is I would go get a bite of Subway after weigh-ins because in the amateurs like you never know where you know you're going to get food or whatever it Subway is just always there.

So they heard that, jumped on it, ended up having a meeting with them and uh did two Super Bowl commercials and 16 total national commercials with them. It was pretty wild. It was like

Key takeaways

  • Lee’s father shaped his discipline, but Lee wants his son to know he can stop when a sport becomes dangerous.
  • Fighting through a broken rib showed Lee the cost of ignoring pain.
  • Lee says the pressure to make his father proud helped him persist through training and injuries.
  • The Caleb Plant fight made Lee recognize how illness and weight cutting had affected his performance.
  • After boxing, Lee built products around CBD, THC, and other ingredients while continuing to focus on health.

Nowhere to Hide

A weekly letter from Ken Rideout about doing the uncomfortable part, and the reasons we use to avoid it.

It starts with 3 Days, 3 Hard Things: one short story from Ken and one hard thing to do, every day for three days. Then one letter a week.